SCHEMBL103719

SCHEMBL103719

Nc1ccc(F)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30428883 1.00
Bromide SCHEMBL5757886 0.97
Hydrochloric Acid SCHEMBL4126368 0.97
Pyridine SCHEMBL27606048 0.85 NOS3 (0.41)
SCHEMBL4024197 0.83 TDO2 (0.46)
SCHEMBL1091572 0.80 PIK3CD (0.57)
SCHEMBL29078057 0.79 MEN1 (0.60)
SCHEMBL29457388 0.79 MEN1 (0.60)
SCHEMBL29966515 0.77
SCHEMBL882102 0.77 FEN1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2580 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119432148-A Perovskite ink, perovskite film and battery device 云南大学 2025-02-14 CN claimed
CN-119384207-A Perovskite precursor solution, perovskite film, preparation method of perovskite precursor solution and perovskite battery 天合光能股份有限公司 2025-01-28 CN claimed
CN-118994106-A Preparation method of diastereoisomer of lebol Lei Sheng 福安药业集团重庆礼邦药物开发有限公司 2024-11-22 CN claimed
CN-118561838-A Preparation method of 5-fluoro-1- (2-fluorophenyl) -1H-pyrazolone [3,4-B ] pyridine-3-carbonitrile 合肥菁科生物科技有限公司 2024-08-30 CN claimed
CN-117654560-B Method for continuously preparing nitro compound by oxidizing amino 安徽泽升科技股份有限公司 2024-06-04 CN claimed
CN-117924347-A Preparation method of monosulfur organosilane coupling agent 江西宏柏新材料股份有限公司 2024-04-26 CN claimed
CN-117654560-A Method for continuously preparing nitro compound by oxidizing amino 安徽泽升科技股份有限公司 2024-03-08 CN claimed
CN-116924975-A Preparation method of 2-amino-5-fluoropyridine 中节能万润股份有限公司 2023-10-24 CN claimed
US-20220402875-A1 S1P3 Antagonists TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 2022-12-22 US claimed
EP-3484865-B1 SOMATOSTATIN MODULATORS AND USES THEREOF CRINETICS PHARMACEUTICALS INC (US) 2022-09-14 EP claimed
EP-1646621-A2 NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN Abbott Laboratories (US) 2006-04-19 EP claimed
US-6949562-B2 Heterocyclic compounds as ligands of the GABAA receptor NEUROGEN CORPORATION (US) 2005-09-27 US claimed
US-20050080095-A1 administering a therapeuitcally effective amount of 3'-(trifluoromethyl)-N-{4-[(trifluoromethyl)sulfonyl]phenyl}-3,6-dihydro-2H-1,2'-bipyridine-4-carboxamide; antagonists of vanilloid receptor subtype I ABBVIE INC. 2005-04-14 US claimed
US-20050065143-A1 Pyridazine derivatives and their use as therapeutic agents XENON PHARMACEUTICALS INC. (CA) 2005-03-24 US claimed
WO-2005007642-A2 NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN ABBOTT LABORATORIES (US) 2005-01-27 WO claimed
US-20040110778-A1 Heterocyclic compounds as ligands of the GABAA receptor YOHANNES DANIEL (US) 2004-06-10 US claimed
EP-1422218-A1 ANTIVIRAL AGENT SHIONOGI & CO., LTD. (JP) 2004-05-26 EP claimed
EP-1325006-A2 HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABA A? RECEPTOR NEUROGEN CORPORATION (US) 2003-07-09 EP claimed
US-20030105081-A1 Heterocyclic compounds as ligands of the GABAA receptor PFIZER INC 2003-06-05 US claimed
WO-2002012442-A2 HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABAA RECEPTOR NEUROGEN CORPORATION (US) 2002-02-14 WO claimed