Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 6/20 | 0.58 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10371976 | 1.00 | TBXAS1 (0.58) | TBXAS1CYP11B2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10373114 | 0.96 | TBXAS1 (0.55) | TBXAS1CYP11B2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10373115 | 0.96 | TBXAS1 (0.55) | TBXAS1CYP11B2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10373826 | 0.89 | TBXAS1 (0.53) | TBXAS1CYP11B2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10373827 | 0.89 | TBXAS1 (0.53) | TBXAS1CYP11B2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10372084 | 0.86 | CYP11B2 (0.57) | TBXAS1CYP11B2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10373326 | 0.85 | TBXAS1 (0.76) | TBXAS1CYP11B2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9768495 | 0.85 | TBXAS1 (0.76) | TBXAS1CYP11B2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10375582 | 0.85 | TBXAS1 (0.76) | TBXAS1CYP11B2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10990799 | 0.84 | CYP11B2 (0.50) | TBXAS1CYP11B2ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129051-B1 | SUBSTITUTED INDOLES | CIBA-GEIGY AG (CH) | 1990-07-04 | — | — | EP | disclosed |
| US-4511573-A | THROMBOXANE SYNTHETASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1985-04-16 | — | — | US | disclosed |
| EP-0129051-A2 | Substituted indoles | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |