Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.46 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135245 | 0.90 | SMARCA2 (0.47) | SMARCA2SMARCA4PBRM1SETD7GPR119 | |
| SCHEMBL135248 | 0.90 | SMARCA2 (0.47) | SMARCA2SMARCA4PBRM1SETD7GPR119 | |
| SCHEMBL135247 | 0.90 | SMARCA2 (0.47) | SMARCA2SMARCA4PBRM1SETD7GPR119 | |
| SCHEMBL135246 | 0.90 | SMARCA2 (0.47) | SMARCA2SMARCA4PBRM1SETD7GPR119 | |
| SCHEMBL3604311 | 0.87 | ALDH1A1 (0.40) | KDM4ENPC1ALDH1A1MAPTHPGD | |
| SCHEMBL3604315 | 0.87 | ALDH1A1 (0.40) | KDM4ENPC1ALDH1A1MAPTHPGD | |
| SCHEMBL3604313 | 0.87 | ALDH1A1 (0.40) | KDM4ENPC1ALDH1A1MAPTHPGD | |
| SCHEMBL103065 | 0.87 | NR1H2 (0.46) | NR1H2GPR119KDM4ENPC1ALDH1A1 | |
| SCHEMBL16549836 | 0.85 | GPR119 (0.39) | NR1H2SETD7GPR119KDM4ENPC1 | |
| SCHEMBL16549837 | 0.85 | GPR119 (0.39) | NR1H2SETD7GPR119KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426113-A1 | CARBINOL COMPOUND HAVING HETEROCYCLIC LINKER | Kowa Company, Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |