SCHEMBL1037313

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1038267	0.97	DRD2 (0.79)	DRD2ADRB2ADRB1HTR1AADRA2A
	SCHEMBL1035947	0.88	DRD2 (0.95)	DRD2ADRB2ADRB1HTR1AADRA2A
	SCHEMBL21166870	0.87	DRD2 (0.77)	DRD2ADRB2ADRB1HTR1AADRA2A
	SCHEMBL1038628	0.86	DRD2 (0.75)	DRD2ADRB2ADRB1HTR1AADRA2A
	Brexpiprazole SCHEMBL29870341	0.86	DRD2 (1.00)	DRD2ADRB2ADRB1HTR1AADRA2A
	Brexpiprazole SCHEMBL1037592	0.86	DRD2 (1.00)	DRD2ADRB2ADRB1HTR1AADRA2A
	Brexpiprazole SCHEMBL29350574	0.86	DRD2 (1.00)	DRD2ADRB2ADRB1HTR1AADRA2A
	Brexpiprazole SCHEMBL14763293	0.85	DRD2 (0.98)	DRD2ADRB2ADRB1HTR1AADRA2A
	Brexpiprazole SCHEMBL1034589	0.85	DRD2 (0.98)	DRD2ADRB2ADRB1HTR1AADRA2A
	Brexpiprazole SCHEMBL15349907	0.85	DRD2 (0.98)	DRD2ADRB2ADRB1HTR1AADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.