Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.49 |
| ▸ | SLC5A2 | P31639 | 6/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | HK1 | P19367 | 1/20 | 0.41 |
| ▸ | HK2 | P52789 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15820816 | 0.86 | SLC5A2 (0.66) | SLC5A2 | |
| SCHEMBL20221046 | 0.86 | SLC5A2 (0.66) | SLC5A2 | |
| SCHEMBL15820814 | 0.86 | SLC5A2 (0.66) | SLC5A2 | |
| SCHEMBL20220854 | 0.86 | SLC5A2 (0.66) | SLC5A2 | |
| SCHEMBL15667202 | 0.85 | KMO (0.47) | KMOCA12CA1CA2CA6 | |
| SCHEMBL9378795 | 0.81 | CYP4F2 (0.50) | CA12CA1CA2CA9 | |
| SCHEMBL9375934 | 0.81 | CYP4F2 (0.50) | CA12CA1CA2CA9 | |
| SCHEMBL10374052 | 0.81 | CYP4F2 (0.50) | CA12CA1CA2CA9 | |
| SCHEMBL8415822 | 0.78 | PLA2G4B (0.44) | KMO | |
| SCHEMBL9753749 | 0.78 | HK1 (0.52) | SLC5A2CA1CA2CA9HK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201823-B1 | NOVEL INTERMEDIATES FOR THE PRODUCTION OF PHARMACEUTICALS | LILLY INDUSTRIES LIMITED (GB) | 1990-12-05 | — | — | EP | disclosed |
| US-4963578-A | LEUKOTRIN ANTAGONISTS; ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1990-10-16 | — | — | US | disclosed |
| US-RE33300-E | LEUKOTRIENE ANTAGONISTS; ANTIALLERGENS | ELI LILLY AND COMPANY (US) | 1990-08-14 | — | — | US | disclosed |
| EP-0134111-B1 | ARALIPHATIC SULPHIDES,SULPHONES AND SULPHOXIDES AND THEIR PHARMACEUTICAL USE | Lilly Industries Limited (GB) | 1988-12-07 | — | — | EP | disclosed |
| US-4665189-A | LEUKOTRIENE ANTAGONISTS | LILLY INDUSTRIES LIMITED (GB) | 1987-05-12 | — | — | US | disclosed |
| EP-0201823-A2 | Novel intermediates for the production of pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1986-11-20 | — | — | EP | disclosed |
| EP-0134111-A1 | Araliphatic sulphides,sulphones and sulphoxides and their pharmaceutical use | Lilly Industries Limited (GB) | 1985-03-13 | — | — | EP | disclosed |