Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416867 | 0.86 | GRM2 (0.52) | CTSK | |
| SCHEMBL15667202 | 0.83 | KMO (0.47) | KMOTP53KMT2A | |
| SCHEMBL379440 | 0.79 | CFTR (0.45) | CTSKTSHR | |
| SCHEMBL27260115 | 0.79 | CFTR (0.45) | CTSKTSHR | |
| SCHEMBL1499434 | 0.79 | CFTR (0.45) | CTSKTSHR | |
| SCHEMBL4624725 | 0.79 | CFTR (0.45) | CTSKTSHR | |
| SCHEMBL10373355 | 0.78 | KMO (0.49) | KMO | |
| SCHEMBL8417334 | 0.76 | F7 (0.41) | PLA2G4BPTPN11 | |
| SCHEMBL8417338 | 0.76 | F7 (0.41) | PLA2G4BPTPN11 | |
| Isophthalic Acid SCHEMBL11324134 | 0.75 | KMT2A (0.58) | PLA2G4BPTPN11PLA2G2ATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990326-A | AN ANTIINFLAMMATORY AGENT AS INHIBITORS OF LEUKOTRIENE HYDROLASE | G.D. SEARLE & CO. (US) | 1999-11-23 | — | — | US | claimed |
| EP-0360246-B1 | 3-Oxiranyl benzoic acids and derivatives thereof | SEARLE & CO (US) | 1994-03-30 | — | — | EP | claimed |
| EP-0360246-A1 | 3-Oxiranyl benzoic acids and derivatives thereof | G.D. Searle & Co. (US) | 1990-03-28 | — | — | EP | claimed |