Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10373886 | 0.87 | EDNRA (0.35) | KDM4EHSD17B10 | |
| SCHEMBL10371933 | 0.84 | CYSLTR2 (0.38) | CYSLTR2CYSLTR1SMPD1PTPN1 | |
| SCHEMBL10372898 | 0.82 | MAPT (0.35) | HSD17B10 | |
| SCHEMBL10371640 | 0.78 | PPARA (0.46) | — | |
| SCHEMBL8225601 | 0.76 | NPC1 (0.43) | KDM4EHSD17B10 | |
| SCHEMBL10375537 | 0.75 | ALDH1A1 (0.36) | KDM4EHSD17B10 | |
| SCHEMBL10373930 | 0.74 | MAPT (0.36) | KDM4EHSD17B10 | |
| SCHEMBL10372259 | 0.73 | MAPT (0.39) | KDM4EHSD17B10 | |
| SCHEMBL10933029 | 0.69 | BRD4 (0.46) | KDM4E | |
| SCHEMBL10372540 | 0.69 | MAPT (0.35) | CYSLTR1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187487-B1 | BENZOTHIOPHENES AND BENZOFURANS HAVING ANTIALLERGIC ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | claimed |
| US-4703053-A | Benzothiophenes and benzofurans and antiallergic use thereof | WARNER-LAMBERT COMPANY (US) | 1987-10-27 | — | — | US | claimed |
| EP-0187487-B1 | BENZOTHIOPHENES AND BENZOFURANS HAVING ANTIALLERGIC ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |
| US-4703053-A | Benzothiophenes and benzofurans and antiallergic use thereof | WARNER-LAMBERT COMPANY (US) | 1987-10-27 | — | — | US | disclosed |
| EP-0187487-A1 | Benzothiophenes and benzofurans having antiallergic activity | WARNER-LAMBERT COMPANY (US) | 1986-07-16 | — | — | EP | disclosed |