Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 5/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10375599 | 1.00 | KCNH2 (0.51) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL10687624 | 1.00 | KCNH2 (0.51) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL10375597 | 1.00 | KCNH2 (0.51) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL10687644 | 1.00 | KCNH2 (0.51) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL10457825 | 0.93 | KCNH2 (0.57) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL10681637 | 0.93 | ALDH1A1 (0.59) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL10375997 | 0.93 | ALDH1A1 (0.59) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL10681621 | 0.93 | ALDH1A1 (0.59) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL8446277 | 0.92 | KDM4E (0.63) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL9376082 | 0.92 | KDM4E (0.63) | KCNH2KDM4EALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4753953-A | Pyridonecarboxylic acid derivatives and antibacterial pharmaceutical compositions thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1988-06-28 | — | — | US | claimed |
| EP-0208210-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |
| US-4753953-A | Pyridonecarboxylic acid derivatives and antibacterial pharmaceutical compositions thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1988-06-28 | — | — | US | disclosed |
| EP-0208210-A1 | Pyridonecarboxylic acid derivatives and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-01-14 | — | — | EP | disclosed |