Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30827640 | 0.79 | POLB (0.41) | MAPTKDM4ENPC1RAB9A | |
| SCHEMBL7051387 | 0.75 | SMN1; SMN2 (0.36) | LMNAHTR2A | |
| SCHEMBL3516279 | 0.74 | MYC (0.30) | MYC | |
| SCHEMBL25712668 | 0.74 | CYP1A2 (0.30) | HTR2A | |
| SCHEMBL5694385 | 0.74 | GRIN2D (0.31) | LMNAMAPTKDM4EGRIN2DGRIN3B | |
| SCHEMBL6217800 | 0.74 | CYP1A2 (0.33) | LMNA | |
| SCHEMBL28247959 | 0.73 | GRIA2 (0.36) | — | |
| SCHEMBL31267970 | 0.73 | HTR3E (0.40) | SIGMAR1KAT2B | |
| SCHEMBL30292820 | 0.73 | SIGMAR1 (0.38) | LMNAMAPTKDM4ESIGMAR1MEN1 | |
| SCHEMBL21815682 | 0.73 | SIGMAR1 (0.38) | LMNAMAPTKDM4ESIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0172058-B1 | PHENYLNAPHTHYRIDINES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, PARTICULARLY AS ANTI-ULCER AGENTS | LABORATOIRES UPSA (FR) | 1990-01-03 | — | — | EP | claimed |