Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10373724 | 0.87 | CNR2 (0.47) | ADORA3ADORA2AADORA1CA12CA1 | |
| SCHEMBL10373370 | 0.87 | ADORA3 (0.50) | ADORA3ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL10374496 | 0.85 | CNR2 (0.45) | ADORA3ADORA2AADORA1ALDH1A1HPGD | |
| SCHEMBL11152052 | 0.83 | ADORA3 (0.61) | ADORA3ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL11020681 | 0.81 | ADORA3 (0.47) | ADORA3ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL11153000 | 0.81 | CNR2 (0.50) | ADORA3ADORA2AADORA1CA12CA1 | |
| SCHEMBL11018894 | 0.81 | ADORA3 (0.49) | ADORA3ADORA2AADORA1CA12CA1 | |
| SCHEMBL11021501 | 0.80 | CNR2 (0.50) | ADORA3ADORA2AADORA1CA12CA1 | |
| SCHEMBL11149173 | 0.80 | CYP3A4 (0.43) | ADORA3ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL11021119 | 0.80 | CNR2 (0.47) | ADORA3ADORA2AADORA1KDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184801-B1 | CHROMENE DERIVATIVE, PROCESS FOR PREPARING THE SAME AND ANTIALLERGIC AGENT CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1990-09-26 | — | — | EP | disclosed |
| US-4731375-A | Coumarin derivatives and antiallergic agents containing the same | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1988-03-15 | — | — | US | disclosed |
| EP-0184801-A1 | Chromene derivative, process for preparing the same and antiallergic agent containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1986-06-18 | — | — | EP | disclosed |