Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 8/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 4/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10375109 | 1.00 | AHR (0.40) | AHRCA2HTR6HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL10376286 | 0.98 | AHR (0.39) | AHRCA2HTR6HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL10376288 | 0.98 | AHR (0.39) | AHRCA2HTR6HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL10377152 | 0.79 | SLC6A2 (0.36) | HTR6HTR2CHTR2BHTR2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL10377153 | 0.79 | SLC6A2 (0.36) | HTR6HTR2CHTR2BHTR2ASLC6A2 | |
| Fluparoxan SCHEMBL7173629 | 0.79 | SLC6A2 (0.38) | CA2HTR6HTR2CHTR1ASLC6A2 | |
| Fluparoxan SCHEMBL9570339 | 0.79 | SLC6A2 (0.38) | CA2HTR6HTR2CHTR1ASLC6A2 | |
| Fluparoxan SCHEMBL29401005 | 0.79 | SLC6A2 (0.38) | CA2HTR6HTR2CHTR1ASLC6A2 | |
| SCHEMBL10375117 | 0.79 | BRD4 (0.36) | HTR6HTR2CHTR2BHTR2ASLC6A2 | |
| Fluparoxan SCHEMBL112164 | 0.79 | SLC6A2 (0.38) | CA2HTR6HTR2CHTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162593-B1 | HETEROCYCLIC AMINO COMPOUNDS | GLAXO GROUP LIMITED (GB) | 1990-08-16 | — | — | EP | claimed |