Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 19/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9667536 | 0.87 | PTAFR (0.70) | PTAFROPRK1PDE4D | |
| SCHEMBL9839073 | 0.85 | PTAFR (0.71) | PTAFROPRK1PDE4D | |
| SCHEMBL8928754 | 0.85 | PTAFR (0.73) | PTAFROPRK1PDE4D | |
| SCHEMBL10514192 | 0.84 | OPRK1 (0.62) | PTAFROPRK1PDE4D | |
| SCHEMBL10375810 | 0.84 | PTAFR (0.66) | PTAFROPRK1PDE4D | |
| SCHEMBL8928417 | 0.84 | PTAFR (0.66) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL10446360 | 0.84 | PTAFR (0.74) | PTAFROPRK1PDE4D | |
| SCHEMBL9673303 | 0.82 | OPRK1 (0.79) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9674052 | 0.82 | PTAFR (0.84) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL8928433 | 0.81 | PTAFR (0.79) | PTAFROPRK1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387613-A1 | Thienodiazepines | BOEHRINGER INGELHEIM KG (DE) | 1990-09-19 | — | — | EP | disclosed |