Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.78 |
| ▸ | MAPT | P10636 | 5/20 | 0.78 |
| ▸ | MAOA | P21397 | 3/20 | 0.71 |
| ▸ | TGM2 | P21980 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.61 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.59 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879552 | 1.00 | MAOB (0.78) | MAOBMAPTMAOATGM2LMNA | |
| SCHEMBL9779399 | 0.88 | MAPT (0.80) | MAOBMAPTMAOATGM2LMNA | |
| SCHEMBL30384809 | 0.88 | MAPT (0.80) | MAOBMAPTMAOATGM2LMNA | |
| SCHEMBL29600935 | 0.88 | MAPT (0.80) | MAOBMAPTMAOATGM2LMNA | |
| SCHEMBL9779404 | 0.88 | MAPT (0.80) | MAOBMAPTMAOATGM2LMNA | |
| SCHEMBL3359800 | 0.87 | MAPT (1.00) | MAOBMAPTMAOATGM2LMNA | |
| SCHEMBL3359803 | 0.87 | MAPT (1.00) | MAOBMAPTMAOATGM2LMNA | |
| SCHEMBL15807305 | 0.86 | MAPT (0.78) | MAOBMAPTMAOATGM2LMNA | |
| SCHEMBL1073090 | 0.86 | MAPT (0.86) | MAOBMAPTTGM2LMNAALDH1A1 | |
| SCHEMBL31441210 | 0.86 | MAPT (0.86) | MAOBMAPTTGM2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228845-B1 | N-CONTAINING HETEROCYCLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4931453-A | CARDIOVASCULAR, HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-06-05 | — | — | US | disclosed |
| US-4857527-A | HYPOTENSIVE, ANTISCHEMIC AGENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| US-4831030-A | FOR CEREBROVASCULAR DISEASES; HYPERTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0110442-B1 | UREA COMPOUNDS, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION, HERBICIDAL AND/OR FUNGICIDAL COMPOSITIONS, AND METHOD OF COMBATING UNDESIRED PLANT GROWTH | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-04-06 | — | — | EP | disclosed |
| EP-0228845-A2 | N-containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-07-15 | — | — | EP | disclosed |