SCHEMBL9779399

SCHEMBL9779399

O=C(/C=C/c1cccc([N+](=O)[O-])c1)c1ccc(O)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 8/20 0.80
▸ MAOB P27338 3/20 0.80
▸ TGM2 P21980 1/20 0.65
▸ LMNA P02545 3/20 0.65
▸ ALDH1A1 P00352 3/20 0.65
▸ CYP1B1 Q16678 2/20 0.63
▸ PTPN1 P18031 1/20 0.62
▸ PTPN12 Q05209 1/20 0.62
▸ PTPN22 Q9Y2R2 1/20 0.62
▸ HSP90AA1 P07900 3/20 0.61
▸ NPSR1 Q6W5P4 3/20 0.61
▸ MITF O75030 2/20 0.61
▸ RECQL P46063 2/20 0.61
▸ RAB9A P51151 1/20 0.61
▸ HTT P42858 1/20 0.61
▸ ATM Q13315 1/20 0.61
▸ HSPD1 P10809 2/20 0.60
▸ HSPE1 P61604 2/20 0.60
▸ MAOA P21397 2/20 0.59
▸ TDP1 Q9NUW8 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9779404 1.00 MAPT (0.80) MAPTMAOBTGM2LMNAALDH1A1
SCHEMBL29600935 1.00 MAPT (0.80) MAPTMAOBTGM2LMNAALDH1A1
SCHEMBL30384809 1.00 MAPT (0.80) MAPTMAOBTGM2LMNAALDH1A1
SCHEMBL3359803 0.89 MAPT (1.00) MAPTMAOBTGM2LMNAALDH1A1
SCHEMBL3359800 0.89 MAPT (1.00) MAPTMAOBTGM2LMNAALDH1A1
SCHEMBL9879552 0.88 MAOB (0.78) MAPTMAOBTGM2LMNAALDH1A1
SCHEMBL10375223 0.88 MAOB (0.78) MAPTMAOBTGM2LMNAALDH1A1
SCHEMBL15807305 0.88 MAPT (0.78) MAPTMAOBTGM2LMNAALDH1A1
SCHEMBL1073092 0.87 MAPT (0.86) MAPTMAOBTGM2LMNAALDH1A1
SCHEMBL31441210 0.87 MAPT (0.86) MAPTMAOBTGM2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
US-5037824-A Cardiotonic, antiischemic agents FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1991-08-06 — — US disclosed
EP-0387070-A2 N-Containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-09-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885MAOB 1004/4885TGM2 1478/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MAOB 2435/4885TGM2 628/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MAOB 2435/4885TGM2 628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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