Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.80 |
| ▸ | MAOB | P27338 | 3/20 | 0.80 |
| ▸ | TGM2 | P21980 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.62 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | MITF | O75030 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.60 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779399 | 1.00 | MAPT (0.80) | MAPTMAOBTGM2LMNAALDH1A1 | |
| SCHEMBL9779404 | 1.00 | MAPT (0.80) | MAPTMAOBTGM2LMNAALDH1A1 | |
| SCHEMBL30384809 | 1.00 | MAPT (0.80) | MAPTMAOBTGM2LMNAALDH1A1 | |
| SCHEMBL3359803 | 0.89 | MAPT (1.00) | MAPTMAOBTGM2LMNAALDH1A1 | |
| SCHEMBL3359800 | 0.89 | MAPT (1.00) | MAPTMAOBTGM2LMNAALDH1A1 | |
| SCHEMBL9879552 | 0.88 | MAOB (0.78) | MAPTMAOBTGM2LMNAALDH1A1 | |
| SCHEMBL10375223 | 0.88 | MAOB (0.78) | MAPTMAOBTGM2LMNAALDH1A1 | |
| SCHEMBL15807305 | 0.88 | MAPT (0.78) | MAPTMAOBTGM2LMNAALDH1A1 | |
| SCHEMBL1073092 | 0.87 | MAPT (0.86) | MAPTMAOBTGM2LMNAALDH1A1 | |
| SCHEMBL31441210 | 0.87 | MAPT (0.86) | MAPTMAOBTGM2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |
| CN-116217461-B | Chalcone derivative containing indole structure and preparation method and application thereof | 贵州大学 | 2024-10-18 | — | — | CN | disclosed |
| CN-117343024-A | Chalcone derivative containing benzoxazole structure and preparation method and application thereof | 贵州大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-116217461-A | Chalcone derivative containing indole structure and preparation method and application thereof | 贵州大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-109251186-B | Chalcone derivative containing benzothiazole, and preparation method and application thereof | 贵州大学 | 2022-04-19 | — | — | CN | disclosed |