Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.65 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 11/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.49 |
| ▸ | ABAT | P80404 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10375322 | 1.00 | GLO1 (0.65) | GLO1GPR35MAPTLMNAMEN1 | |
| SCHEMBL10377446 | 0.90 | GLO1 (0.65) | GLO1GPR35MAPTLMNAMEN1 | |
| SCHEMBL10377445 | 0.90 | GLO1 (0.65) | GLO1GPR35MAPTLMNAMEN1 | |
| SCHEMBL10375324 | 0.87 | GLO1 (0.64) | GLO1GPR35MAPTLMNAMEN1 | |
| SCHEMBL28685595 | 0.86 | GLO1 (0.63) | GLO1MAPTLMNAMEN1KMT2A | |
| SCHEMBL9296374 | 0.81 | GLO1 (0.73) | GLO1MAPTLMNAMEN1KMT2A | |
| SCHEMBL9296381 | 0.81 | GLO1 (0.73) | GLO1MAPTLMNAMEN1KMT2A | |
| SCHEMBL9296584 | 0.81 | GLO1 (0.73) | GLO1MAPTLMNAMEN1KMT2A | |
| SCHEMBL27884554 | 0.81 | GLO1 (0.55) | GLO1MAPTLMNAMEN1KMT2A | |
| SCHEMBL10376451 | 0.80 | EGFR (0.56) | GLO1GPR35MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169712-B1 | NEW PYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND COMPOSITION CONTAINING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4698340-A | TREATMENT OF CEREBROVASCULAR DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0169712-A2 | New pyrimidine derivatives, processes for preparation thereof and composition containing the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-29 | — | — | EP | disclosed |