Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | JUN | P05412 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279215 | 0.88 | GPR35 (0.70) | EGFRGPR35MAPTKDM4EMEN1 | |
| SCHEMBL12211765 | 0.87 | MAPT (0.51) | GLO1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL10673449 | 0.87 | MAPT (0.51) | GLO1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL2213830 | 0.87 | MAPT (0.51) | GLO1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL28685595 | 0.85 | GLO1 (0.63) | GLO1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL16160385 | 0.82 | ALDH1A1 (0.68) | EGFRGPR35MAPTKDM4ELMNA | |
| SCHEMBL10375321 | 0.80 | GLO1 (0.65) | EGFRGLO1GPR35MAPTKDM4E | |
| SCHEMBL10375322 | 0.80 | GLO1 (0.65) | EGFRGLO1GPR35MAPTKDM4E | |
| SCHEMBL2897877 | 0.80 | KMT2A (0.57) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL10671345 | 0.79 | MEN1 (0.50) | GLO1MAPTKDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169712-B1 | NEW PYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND COMPOSITION CONTAINING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4698340-A | TREATMENT OF CEREBROVASCULAR DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0169712-A2 | New pyrimidine derivatives, processes for preparation thereof and composition containing the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-29 | — | — | EP | disclosed |