Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321303 | 0.78 | LMNA (0.32) | LMNA | |
| SCHEMBL1942272 | 0.72 | LMNA (0.37) | LMNA | |
| SCHEMBL10463987 | 0.67 | LMNA (0.33) | LMNA | |
| SCHEMBL3229576 | 0.65 | ELANE (0.46) | HTTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL9721740 | 0.65 | LMNA (0.43) | KMT2ASMN1; SMN2LMNA | |
| SCHEMBL22733768 | 0.65 | LMNA (0.43) | LMNA | |
| SCHEMBL11678651 | 0.63 | HSD11B1 (0.46) | KMT2A | |
| SCHEMBL9876098 | 0.62 | — | — | |
| SCHEMBL4833784 | 0.61 | LMNA (0.40) | LMNA | |
| SCHEMBL5180445 | 0.61 | ELANE (0.51) | KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376870-A1 | A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1990-07-04 | — | — | EP | disclosed |