Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 2/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.45 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.45 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2291563 | 0.80 | DAGLA (0.56) | NUDT1HPSELMNADAGLAPDE5A | |
| SCHEMBL29623058 | 0.80 | DAGLA (0.56) | NUDT1HPSELMNADAGLAPDE5A | |
| SCHEMBL939186 | 0.78 | NUDT1 (0.53) | NUDT1FGFR1FLT1HPSEPARP1 | |
| SCHEMBL3209670 | 0.75 | NUDT1 (0.53) | NUDT1FGFR1FLT1HPSEPARP1 | |
| SCHEMBL14765145 | 0.75 | NUDT1 (0.53) | NUDT1FGFR1FLT1PARP1PDE5A | |
| SCHEMBL1133963 | 0.75 | NUDT1 (0.62) | NUDT1FGFR1FLT1HPSEPARP1 | |
| SCHEMBL880382 | 0.75 | HPGD (0.73) | LMNAGRIN2DGRIN3BGRIK1GRIA1 | |
| SCHEMBL6081154 | 0.74 | GRIN1 (0.45) | LMNAGRIN2DGRIN3BGRIK1GRIA1 | |
| SCHEMBL27832091 | 0.74 | PDE10A (0.57) | NUDT1HPSEDAGLAPDE5AHPGD | |
| SCHEMBL2079832 | 0.73 | DAGLA (0.53) | NUDT1HPSEDAGLAPDE5APRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376870-A1 | A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1990-07-04 | — | — | EP | disclosed |