Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.68 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.68 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ritolukast SCHEMBL38043 | 0.81 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL7710816 | 0.79 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL10375898 | 0.77 | CYSLTR1 (0.67) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL7092704 | 0.77 | CYSLTR1 (0.62) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL8506678 | 0.77 | CYSLTR1 (0.72) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL8506505 | 0.77 | CYSLTR1 (0.81) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL8321128 | 0.76 | CYSLTR1 (0.76) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL10685299 | 0.75 | CYSLTR1 (0.80) | CYSLTR1CYSLTR2 | |
| SCHEMBL9656045 | 0.75 | CYSLTR1 (0.85) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL4848317 | 0.74 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2GPBAR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904786-A | Quinoline compounds as antiallergic and antiinflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-02-27 | — | — | US | disclosed |
| US-4772703-A | LIPOXYGENASE INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |