Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278200 | 0.88 | TRPV1 (0.50) | TRPV1BRD9CYP1A2PDE4BPDE4D | |
| SCHEMBL7269291 | 0.88 | TRPV1 (0.57) | TRPV1BRD9CYP1A2PDE4BPDE4D | |
| SCHEMBL10375042 | 0.86 | TRPV1 (0.54) | TRPV1BRD9CYP1A2PDE4BPDE4D | |
| SCHEMBL617699 | 0.81 | TRPV1 (0.55) | TRPV1CYP1A2PDE4BPDE4DTP53 | |
| SCHEMBL9471488 | 0.81 | TRPV1 (0.50) | TRPV1BRD9CYP1A2PDE4BPDE4D | |
| SCHEMBL9471194 | 0.81 | TRPV1 (0.52) | TRPV1BRD9CYP1A2PDE4BPDE4D | |
| SCHEMBL10375018 | 0.79 | TRPV1 (0.54) | TRPV1BRD9CYP1A2PDE4BPDE4D | |
| SCHEMBL8690052 | 0.79 | TRPV1 (0.48) | TRPV1CYP1A2PDE4BPDE4DTP53 | |
| Hydrochloric Acid SCHEMBL9470737 | 0.77 | TRPV1 (0.47) | TRPV1PDE4BPDE4DMAPT | |
| SCHEMBL29425535 | 0.76 | CTSK (0.52) | TRPV1BRD9CYP1A2PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0172058-B1 | PHENYLNAPHTHYRIDINES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, PARTICULARLY AS ANTI-ULCER AGENTS | LABORATOIRES UPSA (FR) | 1990-01-03 | — | — | EP | claimed |
| US-4622328-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ANTISECRETORY AGENTS | CARPIBEM (FR) | 1986-11-11 | — | — | US | disclosed |