Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691069 | 0.84 | ALDH1A1 (0.45) | PDE4BPDE4DMEN1KMT2ACYP1A2 | |
| SCHEMBL10375042 | 0.81 | TRPV1 (0.54) | TRPV1PDE4BPDE4DCYP1A2MAPT | |
| SCHEMBL8689687 | 0.80 | PDE4B (0.46) | PDE4BPDE4DDHFRALOX5CYP1A2 | |
| SCHEMBL9687088 | 0.80 | PDE4B (0.45) | PDE4BPDE4DDHFRALOX5CYP1A2 | |
| SCHEMBL617699 | 0.79 | TRPV1 (0.55) | TRPV1PDE4BPDE4DMEN1KMT2A | |
| SCHEMBL10376010 | 0.79 | TRPV1 (0.57) | TRPV1PDE4BPDE4DMEN1KMT2A | |
| SCHEMBL10375018 | 0.77 | TRPV1 (0.54) | TRPV1PDE4BPDE4DMEN1KMT2A | |
| SCHEMBL9471194 | 0.76 | TRPV1 (0.52) | TRPV1PDE4BPDE4DMEN1KMT2A | |
| SCHEMBL7269291 | 0.76 | TRPV1 (0.57) | TRPV1PDE4BPDE4DMEN1KMT2A | |
| SCHEMBL7278200 | 0.76 | TRPV1 (0.50) | TRPV1PDE4BPDE4DMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760034-A | ANTIALLERGEN, ANTIINFLAMMATORY, ANTIULCER | SCHERING CORPORATION (US) | 1998-06-02 | — | — | US | disclosed |