Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | IDE | P14735 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10377333 | 0.99 | KMT2A (0.51) | KMT2AMEN1ALDH1A1TP53APAF1 | |
| SCHEMBL10375343 | 0.88 | KMT2A (0.52) | KMT2AMEN1ALDH1A1TP53APAF1 | |
| SCHEMBL10753172 | 0.88 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1APAF1IDE | |
| Hydrochloric Acid SCHEMBL10375298 | 0.87 | KMT2A (0.52) | KMT2AMEN1ALDH1A1TP53APAF1 | |
| SCHEMBL10375250 | 0.87 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1TP53L3MBTL1 | |
| SCHEMBL10756376 | 0.85 | CACNA1D (0.46) | KMT2AMEN1ALDH1A1APAF1IDE | |
| SCHEMBL10377730 | 0.83 | DHFR (0.59) | KMT2AMEN1ALDH1A1HTTPOLB | |
| Hydrochloric Acid SCHEMBL10377356 | 0.80 | POLB (0.42) | KMT2AMEN1ALDH1A1TP53NPSR1 | |
| Hydrochloric Acid SCHEMBL10377365 | 0.77 | KMT2A (0.51) | KMT2AMEN1ALDH1A1TP53HTT | |
| SCHEMBL5340104 | 0.75 | KMT2A (0.86) | KMT2AMEN1ALDH1A1TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169712-B1 | NEW PYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND COMPOSITION CONTAINING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4698340-A | TREATMENT OF CEREBROVASCULAR DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0169712-A2 | New pyrimidine derivatives, processes for preparation thereof and composition containing the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-29 | — | — | EP | disclosed |