Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 4/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049511 | 0.86 | KCNH2 (0.59) | KCNH2HRH3KDM4EALDH1A1HPGD | |
| SCHEMBL10698320 | 0.85 | KCNH2 (0.72) | KCNH2HRH3KDM4EALDH1A1HPGD | |
| SCHEMBL10376134 | 0.85 | KCNH2 (0.54) | KCNH2HRH3KDM4EALDH1A1HPGD | |
| SCHEMBL9048539 | 0.85 | HRH3 (0.53) | KCNH2HRH3KDM4EALDH1A1HPGD | |
| SCHEMBL1858180 | 0.84 | KCNH2 (0.76) | KCNH2HRH3KDM4EALDH1A1HPGD | |
| SCHEMBL9502044 | 0.83 | KCNH2 (0.52) | KCNH2HRH3KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL10443393 | 0.83 | KCNH2 (0.54) | KCNH2HRH3KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL10443267 | 0.83 | KCNH2 (0.54) | KCNH2HRH3KDM4EALDH1A1HPGD | |
| SCHEMBL9411073 | 0.83 | KCNH2 (0.53) | KCNH2HRH3KDM4EALDH1A1HPGD | |
| SCHEMBL10377387 | 0.83 | KCNH2 (0.53) | KCNH2HRH3KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276700-A1 | 8-Cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids, process for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1988-08-03 | — | — | EP | disclosed |