Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Bendiocarb. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.92 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bendiocarb SCHEMBL22080 | 0.96 | ALDH1A1 (1.00) | ALDH1A1LMNAPGRGAAPTGS1 | |
| Bendiocarb SCHEMBL3954562 | 0.96 | ALDH1A1 (1.00) | ALDH1A1LMNAPGRGAAPTGS1 | |
| Bendiocarb SCHEMBL27847663 | 0.96 | ALDH1A1 (1.00) | ALDH1A1LMNAPGRGAAPTGS1 | |
| Bendiocarb SCHEMBL7533636 | 0.95 | ALDH1A1 (0.92) | ALDH1A1LMNAPGRGAAPTGS1 | |
| Bendiocarb SCHEMBL28299657 | 0.91 | ALDH1A1 (0.90) | ALDH1A1LMNAPGRGAAPTGS1 | |
| Bendiocarb SCHEMBL1071011 | 0.86 | ALDH1A1 (0.81) | ALDH1A1LMNAPGRGAAPTGS1 | |
| Bendiocarb SCHEMBL13733255 | 0.81 | ALDH1A1 (0.67) | ALDH1A1LMNAPGRGAAPTGS1 | |
| SCHEMBL17322703 | 0.80 | ALDH1A1 (0.68) | ALDH1A1LMNAMAPK1MTNR1AHTR1A | |
| Bendiocarb SCHEMBL11411962 | 0.78 | ALDH1A1 (0.65) | ALDH1A1LMNAPGRGAAPTGS1 | |
| SCHEMBL10801504 | 0.77 | LMNA (0.68) | ALDH1A1LMNAPGRGAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000005-A1 | MICROENCAPSULATED PESTICIDES WITH A LURE | REDDING BRUCE K JR (US) | 1990-01-11 | — | — | WO | claimed |