Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.43 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.41 |
| ▸ | TFPI | P10646 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10435105 | 0.96 | EPHA2 (0.51) | EPHA2OPRM1OPRK1CALCRLKDM1A | |
| SCHEMBL10378950 | 0.95 | EPHA2 (0.48) | EPHA2OPRM1OPRK1CALCRLKDM1A | |
| SCHEMBL10377176 | 0.89 | EPHA2 (0.49) | EPHA2OPRM1OPRK1CALCRLKDM1A | |
| SCHEMBL8969918 | 0.89 | EPHA2 (0.49) | EPHA2OPRM1CALCRLKDM1ANTSR2 | |
| SCHEMBL10378224 | 0.89 | EPHA2 (0.48) | EPHA2CALCRLKDM1ANTSR2NTSR1 | |
| SCHEMBL7789924 | 0.88 | OPRM1 (0.48) | EPHA2OPRM1OPRK1CXCR4 | |
| SCHEMBL8970642 | 0.87 | EPHA2 (0.47) | EPHA2CALCRLKDM1ANTSR2NTSR1 | |
| SCHEMBL7786086 | 0.87 | OPRM1 (0.45) | EPHA2OPRM1OPRK1CXCR4 | |
| SCHEMBL10434942 | 0.85 | OPRM1 (0.46) | EPHA2OPRM1OPRK1KDM1ATFPI | |
| SCHEMBL7785514 | 0.84 | EPHA2 (0.46) | EPHA2OPRM1OPRK1KDM1ACXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990003180-A1 | PEPTIDES HAVING T CELL SUPPRESSOR ACTIVITY | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1990-04-05 | — | — | WO | disclosed |