Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.48 |
| ▸ | CALCRL | Q16602 | 4/20 | 0.43 |
| ▸ | NTSR2 | O95665 | 6/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 6/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 6/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10378610 | 0.95 | EPHA2 (0.49) | EPHA2CALCRLNTSR2NTSR1SORT1 | |
| SCHEMBL8969918 | 0.94 | EPHA2 (0.49) | EPHA2CALCRLNTSR2NTSR1SORT1 | |
| SCHEMBL10378224 | 0.93 | EPHA2 (0.48) | EPHA2CALCRLNTSR2NTSR1SORT1 | |
| SCHEMBL8970642 | 0.92 | EPHA2 (0.47) | EPHA2CALCRLNTSR2NTSR1SORT1 | |
| SCHEMBL10377176 | 0.91 | EPHA2 (0.49) | EPHA2CALCRLKDM1ACXCR4MAOB | |
| SCHEMBL10435105 | 0.90 | EPHA2 (0.51) | EPHA2CALCRLKDM1ACXCR4OPRM1 | |
| SCHEMBL7785522 | 0.89 | OPRM1 (0.43) | EPHA2NTSR2NTSR1SORT1XIAP | |
| SCHEMBL7788531 | 0.87 | CXCR4 (0.45) | EPHA2NTSR2NTSR1SORT1XIAP | |
| SCHEMBL7785535 | 0.85 | NTSR2 (0.42) | EPHA2NTSR2NTSR1SORT1OPRM1 | |
| SCHEMBL10533153 | 0.85 | EPHA2 (0.49) | EPHA2CALCRLNTSR2NTSR1SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361977-A2 | Peptides having T cell suppressor activity | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1990-04-04 | — | — | EP | claimed |
| WO-1990003180-A1 | PEPTIDES HAVING T CELL SUPPRESSOR ACTIVITY | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1990-04-05 | — | — | WO | disclosed |
| EP-0361977-A2 | Peptides having T cell suppressor activity | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1990-04-04 | — | — | EP | disclosed |