Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.53 |
| ▸ | PRNP | P04156 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10379956 | 0.94 | RXFP1 (0.62) | NCEH1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL19439381 | 0.83 | NCEH1 (0.67) | NCEH1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL27547560 | 0.81 | NCEH1 (0.69) | NCEH1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL11863351 | 0.81 | NCEH1 (0.65) | NCEH1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL11370297 | 0.79 | ALDH1A1 (0.59) | RAB9AHPGDCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL830202 | 0.78 | NCEH1 (1.00) | NCEH1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL829227 | 0.77 | SMN1; SMN2 (1.00) | NCEH1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL3709946 | 0.75 | PRNP (0.71) | NCEH1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL11370296 | 0.73 | ALDH1A1 (0.58) | RAB9AMAPTHPGDCYP1A2HTT | |
| SCHEMBL30448350 | 0.73 | MAPT (0.45) | NCEH1MAPTALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990006372-A1 | SUBSTRATES FOR PEROXIDASE ASSAYING | MICROPROBE CORPORATION (US) | 1990-06-14 | — | — | WO | disclosed |