Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 7/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506888 | 0.83 | ALDH1A1 (0.70) | PRNPRXFP1ALDH1A1HPGDKDM4E | |
| SCHEMBL22169441 | 0.83 | ALDH1A1 (0.70) | PRNPRXFP1ALDH1A1HPGDKDM4E | |
| SCHEMBL27925883 | 0.82 | ALDH1A1 (0.68) | PRNPRXFP1ALDH1A1HPGDKDM4E | |
| SCHEMBL18209401 | 0.81 | TDP1 (0.66) | PRNPRXFP1ALDH1A1HPGDKDM4E | |
| SCHEMBL18209413 | 0.81 | ALDH1A1 (0.66) | PRNPRXFP1ALDH1A1HPGDKDM4E | |
| SCHEMBL6562825 | 0.81 | ALDH1A1 (0.66) | PRNPRXFP1ALDH1A1HPGDKDM4E | |
| SCHEMBL1368627 | 0.80 | RXFP1 (0.64) | PRNPRXFP1ALDH1A1HPGDRAB9A | |
| Naphthyloxyacetic Acid SCHEMBL120838 | 0.80 | KDM4E (1.00) | ALDH1A1HPGDKDM4ETDP1SMN1; SMN2 | |
| Naphthyloxyacetic Acid SCHEMBL29364154 | 0.80 | KDM4E (1.00) | ALDH1A1HPGDKDM4ETDP1SMN1; SMN2 | |
| SCHEMBL2560912 | 0.78 | L3MBTL1 (0.67) | PRNPRXFP1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104276974-B | 1 urea phosphate glycosides acyltransferase inhibitor of N acetylglucosamines and its preparation method and application | 华中农业大学 | 2017-04-05 | — | — | CN | claimed |
| CN-104276974-B | 1 urea phosphate glycosides acyltransferase inhibitor of N acetylglucosamines and its preparation method and application | 华中农业大学 | 2017-04-05 | — | — | CN | disclosed |
| EP-2396295-A1 | PHENOXY ACETIC ACID DERIVATIVES | Merck Serono S.A. (CH) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010092043-A1 | PHENOXY ACETIC ACID DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-08-19 | — | — | WO | disclosed |
| US-6867192-B1 | Compounds useful in the treatment of inflammatory diseases | GLAXO GROUP LIMITED (GB) | 2005-03-15 | — | — | US | disclosed |
| EP-1140837-B1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LTD (GB) | 2004-08-18 | — | — | EP | disclosed |
| EP-1140837-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037444-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2000-06-29 | — | — | WO | disclosed |