Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907725 | 0.94 | SMYD2 (0.37) | SMYD2SMN1; SMN2CYP3A4HTTABL1 | |
| SCHEMBL2144556 | 0.85 | OPRL1 (0.36) | SMYD2SMN1; SMN2CYP3A4HTTABL1 | |
| SCHEMBL2144559 | 0.85 | OPRL1 (0.36) | SMYD2SMN1; SMN2CYP3A4HTTABL1 | |
| SCHEMBL2144555 | 0.85 | OPRL1 (0.36) | SMYD2SMN1; SMN2CYP3A4HTTABL1 | |
| SCHEMBL19689304 | 0.82 | SMYD2 (0.36) | SMYD2SMN1; SMN2CYP3A4HTTABL1 | |
| SCHEMBL10422986 | 0.82 | SMYD2 (0.35) | SMYD2SMN1; SMN2CYP3A4HTT | |
| SCHEMBL13328649 | 0.81 | SMN1; SMN2 (0.39) | SMYD2SMN1; SMN2CYP3A4HTTABL1 | |
| SCHEMBL2908644 | 0.81 | SMN1; SMN2 (0.39) | SMYD2SMN1; SMN2CYP3A4HTTABL1 | |
| SCHEMBL30563837 | 0.81 | DGAT1 (0.38) | SMYD2SMN1; SMN2CYP3A4HTTABL1 | |
| SCHEMBL15404596 | 0.80 | OPRM1 (0.37) | SMYD2SMN1; SMN2CYP3A4HTTABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990005730-A2 | NOVEL CYCLOBUTANE DERIVATIVE AND PROCESS FOR PRODUCING SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1990-05-31 | — | — | WO | disclosed |
| EP-0358154-A2 | Novel cyclobutane derivative and process for producing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1990-03-14 | — | — | EP | disclosed |