Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 15/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 13/20 | 0.59 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.59 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.59 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.59 |
| ▸ | MET | P08581 | 2/20 | 0.59 |
| ▸ | MERTK | Q12866 | 2/20 | 0.57 |
| ▸ | AXL | P30530 | 1/20 | 0.55 |
| ▸ | ATR | Q13535 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488181 | 0.88 | L3MBTL3 (0.60) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL18612197 | 0.86 | MERTK (0.59) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL30454817 | 0.83 | MET (0.57) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL30454036 | 0.83 | MET (0.57) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL488574 | 0.83 | MET (0.57) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL488413 | 0.83 | MET (0.57) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL18611892 | 0.83 | MERTK (0.55) | L3MBTL3L3MBTL1MBTD1TP53BP1MET | |
| SCHEMBL488733 | 0.82 | MET (0.56) | L3MBTL3L3MBTL1METMERTKAXL | |
| SCHEMBL30453025 | 0.82 | MET (0.56) | L3MBTL3L3MBTL1METMERTKAXL | |
| SCHEMBL10217500 | 0.82 | MERTK (0.59) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2476667-A2 | Aminoheteroaryl compounds as protein kinase inhibitors | Sugen, Inc. (US) | 2012-07-18 | — | — | EP | disclosed |