Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946481 | 0.91 | HTR2A (0.46) | ALDH1A1MAPTOPRM1HTR2AOPRD1 | |
| SCHEMBL8946487 | 0.91 | HTR2A (0.46) | ALDH1A1MAPTOPRM1HTR2AOPRD1 | |
| SCHEMBL8946471 | 0.91 | HTR2A (0.46) | ALDH1A1MAPTOPRM1HTR2AOPRD1 | |
| SCHEMBL8946369 | 0.91 | MAPT (0.49) | ALDH1A1MAPTKDM4ELMNAHPGD | |
| SCHEMBL8946357 | 0.91 | MAPT (0.49) | ALDH1A1MAPTKDM4ELMNAHPGD | |
| SCHEMBL8946362 | 0.91 | MAPT (0.49) | ALDH1A1MAPTKDM4ELMNAHPGD | |
| SCHEMBL10381697 | 0.76 | CA1 (0.46) | ALDH1A1MAPTKDM4EHPGDOPRM1 | |
| SCHEMBL8946320 | 0.71 | OPRM1 (0.42) | ALDH1A1MAPTKDM4EHPGDMAPK1 | |
| SCHEMBL8946330 | 0.71 | OPRM1 (0.42) | ALDH1A1MAPTKDM4EHPGDMAPK1 | |
| SCHEMBL8946325 | 0.71 | OPRM1 (0.42) | ALDH1A1MAPTKDM4EHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990015799-A1 | INDENOINDOLE COMPOUNDS II | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |