Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946481 | 1.00 | HTR2A (0.46) | HTR2AOPRM1OPRD1ALDH1A1NPC1 | |
| SCHEMBL8946471 | 1.00 | HTR2A (0.46) | HTR2AOPRM1OPRD1ALDH1A1NPC1 | |
| SCHEMBL10380867 | 0.91 | ALDH1A1 (0.43) | HTR2AOPRM1OPRD1ALDH1A1NPC1 | |
| SCHEMBL10381697 | 0.82 | CA1 (0.46) | HTR2AOPRM1OPRD1ALDH1A1MAPT | |
| SCHEMBL8946330 | 0.78 | OPRM1 (0.42) | OPRM1ALDH1A1MAPTOPRK1 | |
| SCHEMBL8946325 | 0.78 | OPRM1 (0.42) | OPRM1ALDH1A1MAPTOPRK1 | |
| SCHEMBL8946320 | 0.78 | OPRM1 (0.42) | OPRM1ALDH1A1MAPTOPRK1 | |
| SCHEMBL8946494 | 0.78 | MAPT (0.35) | HTR2AALDH1A1MAPT | |
| SCHEMBL8946478 | 0.78 | MAPT (0.35) | HTR2AALDH1A1MAPT | |
| SCHEMBL8946486 | 0.78 | MAPT (0.35) | HTR2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | claimed |
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | claimed |
| EP-0409410-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1991-01-23 | — | — | EP | claimed |
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | disclosed |
| EP-0409410-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1991-01-23 | — | — | EP | disclosed |