Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946974 | 0.81 | HTR2A (0.45) | LMNAMAPTHTR2AOPRM1DRD2 | |
| SCHEMBL8946988 | 0.81 | HTR2A (0.45) | LMNAMAPTHTR2AOPRM1DRD2 | |
| SCHEMBL8946497 | 0.81 | KDM4E (0.43) | HPGDKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8946972 | 0.81 | HTR2A (0.45) | LMNAMAPTHTR2AOPRM1DRD2 | |
| SCHEMBL8946506 | 0.81 | KDM4E (0.43) | HPGDKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8946500 | 0.81 | KDM4E (0.43) | HPGDKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8946368 | 0.80 | MAPT (0.52) | HPGDKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8946364 | 0.80 | MAPT (0.52) | HPGDKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8946374 | 0.80 | MAPT (0.52) | HPGDKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8946341 | 0.80 | HPGD (0.78) | HPGDKDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990015799-A1 | INDENOINDOLE COMPOUNDS II | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | claimed |
| WO-1990015799-A1 | INDENOINDOLE COMPOUNDS II | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |