Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 7/20 | 0.56 |
| ▸ | SLC5A2 | P31639 | 7/20 | 0.55 |
| ▸ | SLC28A3 | Q9HAS3 | 5/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1036196 | 0.92 | SLC5A2 (0.52) | SLC5A1SLC5A2SLC28A3KDM4EMAPT | |
| SCHEMBL1038365 | 0.89 | SLC5A2 (0.66) | SLC5A1SLC5A2SLC28A3TYRACHE | |
| SCHEMBL1039839 | 0.81 | SLC5A2 (0.49) | SLC5A1SLC5A2SLC28A3 | |
| SCHEMBL1038208 | 0.81 | SLC5A2 (0.47) | SLC5A1SLC5A2SLC28A3 | |
| SCHEMBL1037757 | 0.81 | SLC5A2 (0.58) | SLC5A1SLC5A2SLC28A3TYREPHX2 | |
| SCHEMBL1037703 | 0.79 | SLC5A2 (0.59) | SLC5A1SLC5A2SLC28A3TYRACHE | |
| SCHEMBL1038545 | 0.77 | SLC5A2 (0.45) | SLC5A1SLC5A2SLC28A3TYR | |
| SCHEMBL13107677 | 0.72 | SLC5A2 (0.72) | SLC5A1SLC5A2TYRACHE | |
| SCHEMBL2583297 | 0.72 | SLC5A2 (0.80) | SLC5A1SLC5A2SLC28A3TYR | |
| SCHEMBL1726677 | 0.71 | SLC5A1 (0.56) | SLC5A1SLC5A2SLC28A3TYRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1849795-B1 | 1-SUBSTITUTED-7-( -D-GLYCOPYRANOSYLOXY)(AZA)INDOLE COMPOUND AND PHARMACEUTICAL CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2011-01-26 | — | — | EP | claimed |
| EP-1849795-B1 | 1-SUBSTITUTED-7-( -D-GLYCOPYRANOSYLOXY)(AZA)INDOLE COMPOUND AND PHARMACEUTICAL CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2011-01-26 | — | — | EP | disclosed |
| US-7749972-B2 | 1-substituted-7-(β-D-glycopyranosyloxy)(aza)indole compound and pharmaceutical containing the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-07-06 | — | — | US | disclosed |
| US-7749972-B2 | 1-substituted-7-(β-D-glycopyranosyloxy)(aza)indole compound and pharmaceutical containing the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-07-06 | — | — | US | disclosed |
| US-7749972-B2 | 1-substituted-7-(β-D-glycopyranosyloxy)(aza)indole compound and pharmaceutical containing the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-07-06 | — | — | US | disclosed |
| US-20090054356-A1 | 1-SUBSTITUTED-7-(B-D-GLYCOPYRANOSYLOXY)(AZA)INDOLE COMPOUND AND PHARMACEUTICAL CONTAINING THE SAME | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20090054356-A1 | 1-SUBSTITUTED-7-(B-D-GLYCOPYRANOSYLOXY)(AZA)INDOLE COMPOUND AND PHARMACEUTICAL CONTAINING THE SAME | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20090054356-A1 | 1-SUBSTITUTED-7-(B-D-GLYCOPYRANOSYLOXY)(AZA)INDOLE COMPOUND AND PHARMACEUTICAL CONTAINING THE SAME | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| EP-1849795-A1 | 1-SUBSTITUTED-7-( -D-GLYCOPYRANOSYLOXY)(AZA)INDOLE COMPOUND AND PHARMACEUTICAL CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054356-A1 | 1-SUBSTITUTED-7-(B-D-GLYCOPYRANOSYLOXY)(AZA)INDOLE COMPOUND AND PHARMACEUTICAL CONTAINING THE SAME | SLC5A1, SLC5A2, GPR119 | SLC5A1 1/4885SLC5A2 2/4885SLC28A3 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.