SCHEMBL1039839

SCHEMBL1039839

OC[C@H]1O[C@@H](Oc2cccc3ccn(Cc4ccccc4)c23)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 10/20 0.49
▸ CD209 Q9NNX6 1/20 0.48
▸ ATM Q13315 1/20 0.47
▸ SLC28A3 Q9HAS3 2/20 0.47
▸ SLC5A1 P13866 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1037757 0.91 SLC5A2 (0.58) SLC5A2CD209SLC28A3SLC5A1
SCHEMBL1036196 0.89 SLC5A2 (0.52) SLC5A2CD209ATMSLC28A3SLC5A1
SCHEMBL1037703 0.89 SLC5A2 (0.59) SLC5A2SLC28A3SLC5A1
SCHEMBL1038545 0.86 SLC5A2 (0.45) SLC5A2CD209SLC28A3SLC5A1
SCHEMBL1038103 0.81 SLC5A1 (0.56) SLC5A2SLC28A3SLC5A1
SCHEMBL1038365 0.79 SLC5A2 (0.66) SLC5A2SLC28A3SLC5A1
SCHEMBL23479818 0.75 CD209 (0.70) SLC5A2CD209ATMSLC28A3SLC5A1
SCHEMBL4609196 0.75 CD209 (0.70) SLC5A2CD209ATMSLC28A3SLC5A1
SCHEMBL1004201 0.75 CD209 (0.70) SLC5A2CD209ATMSLC28A3SLC5A1
SCHEMBL8654258 0.75 CD209 (0.70) SLC5A2CD209ATMSLC28A3SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1849795-B1 1-SUBSTITUTED-7-( -D-GLYCOPYRANOSYLOXY)(AZA)INDOLE COMPOUND AND PHARMACEUTICAL CONTAINING THE SAME KISSEI PHARMACEUTICAL (JP) 2011-01-26 — — EP claimed
US-7749972-B2 1-substituted-7-(β-D-glycopyranosyloxy)(aza)indole compound and pharmaceutical containing the same KISSEI PHARMACEUTICAL CO., LTD. (JP) 2010-07-06 — — US disclosed
US-7749972-B2 1-substituted-7-(β-D-glycopyranosyloxy)(aza)indole compound and pharmaceutical containing the same KISSEI PHARMACEUTICAL CO., LTD. (JP) 2010-07-06 — — US disclosed
US-20090054356-A1 1-SUBSTITUTED-7-(B-D-GLYCOPYRANOSYLOXY)(AZA)INDOLE COMPOUND AND PHARMACEUTICAL CONTAINING THE SAME KISSEI PHARMACEUTICAL CO., LTD. (JP) 2009-02-26 — — US disclosed
US-20090054356-A1 1-SUBSTITUTED-7-(B-D-GLYCOPYRANOSYLOXY)(AZA)INDOLE COMPOUND AND PHARMACEUTICAL CONTAINING THE SAME KISSEI PHARMACEUTICAL CO., LTD. (JP) 2009-02-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054356-A1 1-SUBSTITUTED-7-(B-D-GLYCOPYRANOSYLOXY)(AZA)INDOLE COMPOUND AND PHARMACEUTICAL CONTAINING THE SAME SLC5A1, SLC5A2, GPR119 SLC5A2 2/4885CD209 1761/4885ATM 4742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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