Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 2/20 | 0.48 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | NPY4R | P50391 | 1/20 | 0.47 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 10/20 | 0.45 |
| ▸ | CTSD | P07339 | 2/20 | 0.45 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10381547 | 1.00 | FURIN (0.48) | FURINPCSK6NPY1RNPY2RNPY4R | |
| SCHEMBL29384387 | 0.96 | NTSR2 (0.45) | FURINPCSK6NPY1RNPY2RNPY4R | |
| SCHEMBL29531524 | 0.96 | NTSR2 (0.45) | FURINPCSK6NPY1RNPY2RNPY4R | |
| SCHEMBL29520932 | 0.93 | BACE1 (0.53) | FURINPCSK6BACE1CTSDBACE2 | |
| SCHEMBL29682467 | 0.93 | NPY4R (0.52) | NPY1RNPY2RNPY4RNTSR2NTSR1 | |
| SCHEMBL29368320 | 0.92 | BACE1 (0.51) | NTSR2NTSR1BACE1CTSDBACE2 | |
| SCHEMBL29630480 | 0.92 | NTSR2 (0.46) | FURINPCSK6NPY1RNPY2RNPY4R | |
| SCHEMBL29630471 | 0.91 | NPY4R (0.53) | NPY1RNPY2RNPY4RNTSR2NTSR1 | |
| SCHEMBL31193414 | 0.91 | ERAP2 (0.50) | FURINPCSK6NPY1RNPY2RNPY4R | |
| SCHEMBL6700436 | 0.90 | GSR (0.45) | FURINPCSK6BACE1CTSDERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990012031-A1 | SOLUBLE CD4 PRODUCED IN $i(E. COLI) | THE UPJOHN COMPANY (US) | 1990-10-18 | — | — | WO | disclosed |