Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.43 |
| ▸ | FURIN | P09958 | 4/20 | 0.43 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | NMT2 | O60551 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700441 | 1.00 | GSR (0.45) | GSRDPP8DPP9DPP7CPB2 | |
| SCHEMBL30894714 | 0.92 | FURIN (0.45) | GSRDPP8DPP9DPP7CPB2 | |
| SCHEMBL29630321 | 0.92 | CTSD (0.48) | GSRDPP8DPP9DPP7CPB2 | |
| SCHEMBL29630423 | 0.92 | FURIN (0.45) | GSRDPP8DPP9DPP7CPB2 | |
| SCHEMBL4270981 | 0.92 | FOLH1 (0.48) | GSRDPP8DPP9DPP7CPB2 | |
| SCHEMBL4270994 | 0.92 | FOLH1 (0.48) | GSRDPP8DPP9DPP7CPB2 | |
| SCHEMBL11249367 | 0.91 | FOLH1 (0.52) | GSRDPP8DPP9DPP7CPB2 | |
| SCHEMBL30436412 | 0.91 | FOLH1 (0.47) | GSRDPP8DPP9DPP7CPB2 | |
| SCHEMBL31722025 | 0.90 | GSR (0.55) | GSRDPP8DPP9DPP7CPB2 | |
| SCHEMBL22612668 | 0.90 | GSR (0.55) | GSRDPP8DPP9DPP7CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040013683-A1 | Derivatives of soluble T-4 | THE TRUSTEES OF COLUMBIA UNIVERSITY (US) | 2004-01-22 | — | — | US | disclosed |
| US-6673896-B1 | PROTEIN WHICH COMPLEXES WITH HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE GLYCOPROTEIN | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2004-01-06 | — | — | US | disclosed |
| WO-1989008143-A1 | DERIVATIVES OF SOLUBLE T-4 | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF (US) | 1989-09-08 | — | — | WO | disclosed |