SCHEMBL29368320

SCHEMBL29368320

CC(C)C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCCN)C(C)C)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 16/20 0.51
BACE2 Q9Y5Z0 4/20 0.51
CTSD P07339 4/20 0.51
NTSR2 O95665 1/20 0.43
NTSR1 P30989 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9848654 0.96 BACE1 (0.55) BACE1BACE2CTSD
SCHEMBL29387347 0.96 BACE1 (0.51) BACE1BACE2CTSD
SCHEMBL29531524 0.93 NTSR2 (0.45) BACE1BACE2CTSDNTSR2NTSR1
SCHEMBL29384387 0.93 NTSR2 (0.45) BACE1BACE2CTSDNTSR2NTSR1
SCHEMBL10381547 0.92 FURIN (0.48) BACE1BACE2CTSDNTSR2NTSR1
SCHEMBL30242247 0.92 GNPAT (0.49) BACE1BACE2CTSD
SCHEMBL10381550 0.92 FURIN (0.48) BACE1BACE2CTSDNTSR2NTSR1
SCHEMBL29455900 0.92 NPY1R (0.46) BACE1BACE2CTSD
SCHEMBL31110645 0.91 ENPEP (0.46) BACE1
SCHEMBL30578953 0.90 BACE1 (0.49) BACE1BACE2CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113710807-B Microorganisms and methods for producing oxygenates from hexoses 布拉斯科公司 2025-05-30 CN disclosed
CN-114008197-B Metabolic engineering for simultaneous consumption of xylose and glucose to produce chemicals from second generation sugars 布拉斯科公司 2025-05-27 CN disclosed
CN-113584015-B Formation of synthons 新英格兰生物实验室公司 2025-05-02 CN disclosed
CN-113287013-B Method for examining ulcerative colitis and primary sclerosing cholangitis 国立大学法人京都大学 2025-04-15 CN disclosed
CN-112262215-B Chimeric vectors 美国卫生和人力服务部 2025-03-18 CN disclosed
CN-114096666-B Compositions and methods for treating heme lesions 比姆医疗股份有限公司 2025-03-18 CN disclosed
CN-114875012-B Engineered CRISPR-Cas9 nucleases 通用医疗公司 2025-02-18 CN disclosed
WO-2025029727-A2 COMPOSITIONS, METHODS, AND SYSTEMS FOR DNA MODIFICATION THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2025-02-06 WO disclosed
CN-113614104-B Viral vectors encoding recombinant FVIII variants with increased expression for gene therapy of hemophilia A 百深公司 2025-01-10 CN disclosed
CN-113655228-B Immunoassay method for detecting cleaved high molecular weight kininogen 武田药品工业株式会社 2025-01-07 CN disclosed
CN-108728477-B Efficient transposition mutation system and construction method 华东理工大学 2022-02-22 CN disclosed
CN-111358799-B Application of ginsenoside CK as lipid-lowering and weight-losing medicine 东北师范大学 2022-02-18 CN disclosed
CN-107406510-B Prostate antigen standard substance and application thereof 欧普科诊断有限责任公司 2022-02-18 CN disclosed
CN-114045305-A Multi-swivel subsystem 深圳市深研生物科技有限公司 2022-02-15 CN disclosed
CN-114045270-A Method for producing ginsenoside Rg1 and special engineering bacteria thereof 中国科学院天津工业生物技术研究所 2022-02-15 CN disclosed
CN-107406864-B Method for producing L-serine using genetically engineered microorganisms lacking serine degradation pathway 化学生物有限公司 2022-02-11 CN disclosed
CN-114015675-A Lambda-carrageenase OUC-LuV and application thereof 中国海洋大学 2022-02-08 CN disclosed
CN-114008197-A Metabolic engineering for simultaneous consumption of xylose and glucose to produce chemicals from second generation sugars 布拉斯科公司 2022-02-01 CN disclosed
CN-114007637-A Recombinant factor VIII-FC for treatment of hemophilia and low bone mineral density 比奥维拉迪维治疗股份有限公司 2022-02-01 CN disclosed
CN-111879940-B Pulmonary tuberculosis marker and application 中国科学院微生物研究所 2022-02-01 CN disclosed