Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.65 |
| ▸ | PGR | P06401 | 2/20 | 0.65 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | AR | P10275 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.58 |
| ▸ | SHBG | P04278 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9836539 | 0.99 | HIF1A (0.64) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL9835911 | 0.88 | HIF1A (0.71) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL9838110 | 0.87 | HIF1A (0.65) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL9836440 | 0.87 | HIF1A (0.49) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL18278997 | 0.85 | HIF1A (0.80) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL29546250 | 0.85 | HIF1A (0.65) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL12397331 | 0.82 | HIF1A (0.74) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL13692155 | 0.81 | HIF1A (0.79) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL8722422 | 0.81 | HIF1A (0.73) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL8722429 | 0.81 | HIF1A (0.73) | HIF1APGRSERPINA6LMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990008128-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | BUNDGAARD HANS (DK) | 1990-07-26 | — | — | WO | disclosed |