Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 12/20 | 0.49 |
| ▸ | PGR | P06401 | 5/20 | 0.49 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | IL6 | P05231 | 1/20 | 0.44 |
| ▸ | GLUL | P15104 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838110 | 0.89 | HIF1A (0.65) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL9836144 | 0.89 | HIF1A (0.54) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL10381829 | 0.87 | HIF1A (0.65) | HIF1APGRSERPINA6LMNAAR | |
| Hydrochloric Acid SCHEMBL9836539 | 0.86 | HIF1A (0.64) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL10700873 | 0.80 | HIF1A (0.64) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL13232 | 0.80 | HIF1A (0.74) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL10883182 | 0.79 | HIF1A (0.59) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL10527431 | 0.79 | HIF1A (0.62) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL1513910 | 0.78 | HIF1A (0.61) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL5087747 | 0.77 | HIF1A (0.70) | HIF1APGRSERPINA6LMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454773-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | Bundgaard, Hans (DK) | 1991-11-06 | — | — | EP | disclosed |
| WO-1990008128-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | BUNDGAARD HANS (DK) | 1990-07-26 | — | — | WO | disclosed |