Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978284 | 0.80 | CARM1 (0.51) | KCNA3CARM1PRMT6SIGMAR1KDM4E | |
| SCHEMBL7979644 | 0.76 | DRD2 (0.50) | — | |
| SCHEMBL10382960 | 0.76 | CHRM2 (0.58) | SIGMAR1CYP2D6HTR2AHTR2CSLC6A2 | |
| Hydrochloric Acid SCHEMBL9353077 | 0.76 | KDM1A (0.46) | KCNA3SIGMAR1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL7965918 | 0.75 | CHRM2 (0.51) | KDM4ECYP2D6HTR2AHTR2CSLC6A2 | |
| Hydrochloric Acid SCHEMBL9353093 | 0.74 | KDM1A (0.48) | KCNA3SIGMAR1CYP1A2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9356760 | 0.73 | MAPK1 (0.53) | KDM4ECYP2D6TSHRHTR2AHTR2C | |
| SCHEMBL10382466 | 0.73 | CYP2D6 (0.36) | CYP2D6HTR2AHTR2CSLC6A3 | |
| SCHEMBL10382462 | 0.72 | HTR7 (0.56) | — | |
| Hydrochloric Acid SCHEMBL9352871 | 0.71 | HRH1 (0.55) | CYP1A2CYP3A4CYP2D6HTR2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968705-A | ANTIINFLAMMATORY AGENTS FOR RESPIRATORY SYSTEM DISORDERS | ADIR ET CIE (FR) | 1990-11-06 | — | — | US | disclosed |