Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PEPD | P12955 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385067 | 0.90 | ACE (0.44) | ACELMNASMN1; SMN2RENKDM4E | |
| SCHEMBL10383381 | 0.89 | ACE (0.42) | ACELMNASMN1; SMN2RENKDM4E | |
| Maleic Acid SCHEMBL10383733 | 0.86 | SMN1; SMN2 (0.47) | ACELMNASMN1; SMN2RENKDM4E | |
| SCHEMBL7271796 | 0.80 | ACE (0.66) | ACELMNASMN1; SMN2RENKDM4E | |
| SCHEMBL683465 | 0.79 | ACE (0.73) | ACELMNASMN1; SMN2RENKDM4E | |
| SCHEMBL10385069 | 0.78 | MEN1 (0.40) | ACEMAPTHSD17B10ACE2 | |
| SCHEMBL10796062 | 0.78 | ACE (0.59) | ACELMNASMN1; SMN2RENKDM4E | |
| SCHEMBL10796436 | 0.78 | ACE (0.59) | ACELMNASMN1; SMN2RENKDM4E | |
| SCHEMBL10796078 | 0.78 | ACE (0.59) | ACELMNASMN1; SMN2RENKDM4E | |
| SCHEMBL10796279 | 0.78 | ACE (0.59) | ACELMNASMN1; SMN2RENKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977179-A | Inhibiting angiotensin converting enzyme | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-12-11 | — | — | US | disclosed |