Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.35 |
| ▸ | PEPD | P12955 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL10383733 | 0.95 | SMN1; SMN2 (0.47) | ACELMNASMN1; SMN2FKBP1APEPD | |
| SCHEMBL10385067 | 0.91 | ACE (0.44) | ACELMNASMN1; SMN2FKBP1APEPD | |
| SCHEMBL10383406 | 0.89 | ACE (0.53) | ACELMNASMN1; SMN2PEPDACE2 | |
| SCHEMBL10779744 | 0.81 | ACE (0.52) | ACELMNASMN1; SMN2FKBP1APEPD | |
| SCHEMBL10383380 | 0.80 | ACE (0.46) | ACELMNASMN1; SMN2FKBP1AMEN1 | |
| SCHEMBL10383374 | 0.79 | MEN1 (0.37) | ACEMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL10384071 | 0.78 | L3MBTL1 (0.35) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL10521977 | 0.78 | ACE (0.44) | ACELMNASMN1; SMN2FKBP1AMEN1 | |
| SCHEMBL10521974 | 0.78 | ACE (0.44) | ACELMNASMN1; SMN2FKBP1AMEN1 | |
| SCHEMBL10779423 | 0.77 | ACE (0.43) | ACELMNASMN1; SMN2PEPDACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977179-A | Inhibiting angiotensin converting enzyme | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-12-11 | — | — | US | disclosed |