Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PEPD | P12955 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.38 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10383381 | 0.91 | ACE (0.42) | ACELMNAPEPDSMN1; SMN2FKBP1A | |
| SCHEMBL10383406 | 0.90 | ACE (0.53) | ACELMNAPEPDSMN1; SMN2ACE2 | |
| Maleic Acid SCHEMBL10383733 | 0.86 | SMN1; SMN2 (0.47) | ACELMNAPEPDSMN1; SMN2FKBP1A | |
| SCHEMBL10385066 | 0.77 | ACE (0.49) | ACELMNAPEPDSMN1; SMN2FKBP1A | |
| SCHEMBL10385091 | 0.75 | ACE (0.49) | ACELMNAPEPDSMN1; SMN2FKBP1A | |
| SCHEMBL10385089 | 0.75 | ACE (0.49) | ACELMNAPEPDSMN1; SMN2FKBP1A | |
| SCHEMBL10384321 | 0.75 | MEN1 (0.38) | ACESMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL18088507 | 0.74 | PEPD (0.47) | ACELMNAPEPDSMN1; SMN2FKBP1A | |
| SCHEMBL10385069 | 0.74 | MEN1 (0.40) | ACEACE2MAPTHSD17B10 | |
| SCHEMBL10383387 | 0.74 | ACE (0.48) | ACELMNAPEPDSMN1; SMN2FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977179-A | Inhibiting angiotensin converting enzyme | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-12-11 | — | — | US | claimed |
| US-4977179-A | Inhibiting angiotensin converting enzyme | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-12-11 | — | — | US | disclosed |