Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FABP2 | P12104 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10384845 | 0.86 | CYP3A4 (0.45) | ALDH1A1HPGDPOLBKDM4EGAA | |
| SCHEMBL10383395 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HPGDPOLBKDM4EGAA | |
| SCHEMBL10388967 | 0.82 | GAA (0.46) | ALDH1A1HPGDKDM4EGAAPKM | |
| SCHEMBL10383133 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HPGDPOLBKDM4EGAA | |
| SCHEMBL12301838 | 0.78 | POLB (0.59) | ALDH1A1HPGDPOLBKDM4ELMNA | |
| SCHEMBL9806945 | 0.77 | GAA (0.49) | ALDH1A1HPGDPOLBKDM4EGAA | |
| SCHEMBL9818418 | 0.74 | ALDH1A1 (0.51) | ALDH1A1HPGDPOLBKDM4EGAA | |
| SCHEMBL10384851 | 0.74 | TSHR (0.43) | ALDH1A1HPGDPOLBGAAKMT2A | |
| SCHEMBL9806965 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HPGDPOLBKDM4EGAA | |
| SCHEMBL8958777 | 0.74 | POLB (0.47) | ALDH1A1POLBKDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906740-A | Monoazo dyes containing as the azo component A phenylsulfonylphenyl radical | CIBA-GEIGY CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |