Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 2/20 | 0.38 |
| ▸ | FLT4 | P35916 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10384851 | 0.87 | TSHR (0.43) | CYP3A4HPGDPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL10383848 | 0.86 | ALDH1A1 (0.44) | HPGDPOLBLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10383133 | 0.86 | ALDH1A1 (0.42) | HPGDPOLBLMNAALDH1A1GAA | |
| SCHEMBL9806945 | 0.84 | GAA (0.49) | HPGDPOLBLMNAALDH1A1GAA | |
| SCHEMBL12301838 | 0.82 | POLB (0.59) | CYP3A4HPGDPOLBLMNAALDH1A1 | |
| SCHEMBL10383395 | 0.81 | ALDH1A1 (0.49) | HPGDPOLBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9806965 | 0.81 | ALDH1A1 (0.42) | CYP3A4HPGDPOLBLMNAALDH1A1 | |
| SCHEMBL3278551 | 0.79 | POLB (0.51) | CYP3A4POLBALDH1A1HSD11B1GAA | |
| SCHEMBL5261746 | 0.78 | MEN1 (0.57) | CYP3A4POLBALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL12450093 | 0.78 | LMNA (0.48) | HPGDPOLBLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906740-A | Monoazo dyes containing as the azo component A phenylsulfonylphenyl radical | CIBA-GEIGY CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |