Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1751614 | 0.87 | SLC6A3 (0.65) | SLC6A2SLC6A4SLC6A3DHODHCFTR | |
| SCHEMBL1751726 | 0.87 | SLC6A3 (0.60) | SLC6A2SLC6A4SLC6A3DHODHFABP4 | |
| SCHEMBL1752157 | 0.87 | SLC6A3 (0.65) | SLC6A2SLC6A4SLC6A3DHODHCFTR | |
| SCHEMBL4350872 | 0.87 | SLC6A3 (0.65) | SLC6A2SLC6A4SLC6A3DHODHCFTR | |
| SCHEMBL1752156 | 0.87 | SLC6A3 (0.65) | SLC6A2SLC6A4SLC6A3DHODHCFTR | |
| SCHEMBL1751676 | 0.87 | SLC6A3 (0.65) | SLC6A2SLC6A4SLC6A3DHODHCFTR | |
| SCHEMBL4350863 | 0.87 | SLC6A3 (0.65) | SLC6A2SLC6A4SLC6A3DHODHCFTR | |
| SCHEMBL8905393 | 0.79 | CFTR (0.50) | SLC6A2SLC6A4SLC6A3DHODHCFTR | |
| SCHEMBL17927933 | 0.77 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3DHODHCFTR | |
| SCHEMBL10369788 | 0.77 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3DHODHCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4954583-A | Arylcyclobutene carboxylate esters | SHELL OIL COMPANY (US) | 1990-09-04 | — | — | US | disclosed |
| US-4954584-A | Thermosetting resin compositions | SHELL OIL COMPANY (US) | 1990-09-04 | — | — | US | disclosed |