Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.65 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1751676 | 1.00 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4DHODHFABP4 | |
| SCHEMBL4350863 | 1.00 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4DHODHFABP4 | |
| SCHEMBL1752156 | 1.00 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4DHODHFABP4 | |
| SCHEMBL1751614 | 1.00 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4DHODHFABP4 | |
| SCHEMBL1752157 | 1.00 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4DHODHFABP4 | |
| SCHEMBL1751726 | 0.96 | SLC6A3 (0.60) | SLC6A3SLC6A2SLC6A4DHODHFABP4 | |
| SCHEMBL10384372 | 0.87 | SLC6A2 (0.50) | SLC6A3SLC6A2SLC6A4DHODHFABP4 | |
| SCHEMBL4350867 | 0.85 | SLC6A3 (0.71) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL17972851 | 0.84 | SLC6A3 (0.61) | SLC6A3SLC6A2SLC6A4FGF23PTGS2 | |
| SCHEMBL6692371 | 0.84 | SLC6A3 (0.57) | SLC6A3SLC6A2SLC6A4DHODHFGF23 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029541-A1 | PROCESS FOR PREPARATION OF ENANTIOMERICALLY ENRICHED CYCLIC BETA-ARYL OR HETEROARYL CARBOXYLIC ACIDS | F. Hoffmann-Roche AG (CH) | 2009-03-04 | — | — | EP | claimed |
| WO-2007113155-A1 | PROCESS FOR PREPARATION OF ENANTIOMERICALLY ENRICHED CYCLIC Β-ARYL OR HETEROARYL CARBOXYLIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-10-11 | — | — | WO | claimed |