Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PEPD | P12955 | 2/20 | 0.38 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10383403 | 0.91 | ACE (0.58) | ACELMNASMN1; SMN2PEPDACE2 | |
| SCHEMBL10383380 | 0.90 | ACE (0.46) | ACELMNASMN1; SMN2ACE2FKBP1A | |
| SCHEMBL10385089 | 0.87 | ACE (0.49) | ACELMNASMN1; SMN2PEPDXPNPEP1 | |
| SCHEMBL10385091 | 0.87 | ACE (0.49) | ACELMNASMN1; SMN2PEPDXPNPEP1 | |
| Maleic Acid SCHEMBL10383732 | 0.86 | SMN1; SMN2 (0.51) | ACELMNASMN1; SMN2ACE2FKBP1A | |
| SCHEMBL10384139 | 0.85 | ACE (0.48) | ACELMNASMN1; SMN2PEPDXPNPEP1 | |
| SCHEMBL10383387 | 0.85 | ACE (0.48) | ACELMNASMN1; SMN2PEPDXPNPEP1 | |
| SCHEMBL10385088 | 0.85 | ACE (0.51) | ACELMNASMN1; SMN2PEPDXPNPEP1 | |
| SCHEMBL10385087 | 0.85 | ACE (0.51) | ACELMNASMN1; SMN2PEPDXPNPEP1 | |
| SCHEMBL10522615 | 0.83 | ACE (0.48) | ACELMNASMN1; SMN2ACE2FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977179-A | Inhibiting angiotensin converting enzyme | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-12-11 | — | — | US | claimed |
| US-4977179-A | Inhibiting angiotensin converting enzyme | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-12-11 | — | — | US | disclosed |